AlloDerm tympanoplasty of tympanic membrane perforations

Photographs of the inferior one half of the tympanic membrane after tympanoplasty. AlloDerm at (A) 4 weeks and (B) 10 weeks. Fascia at (C) 4 weeks and (D) 10 weeks. Notice the blood vessels overlying the grafts at 4 weeks; the vessels are less noticeable by the 10th week. Graft thinning is also apparent between 4 and 10 weeks.

Tympanic membrane with AlloDerm graft (H&E stain, original magnification × 200). Lateral surface at top and medial surface at bottom of photograph. Disorderly arranged collagen fibers occupy the medial two thirds of the TM. Fibroblast infiltration and neovascularization is appreciated, as well as epithelial and mucosal cell coverage on opposing surfaces of the graft.