*; Janet S. Winston, MD†; Gustavo Diaz-Reyes; Thom R. Loree, MD*; Larry Myers, MD; M.Abraham Kuriakose, MD†; Nestor R. Rigual, MD; Wesley L. Hicks, MD†">
Ameloblastic carcinoma: Report of an aggressive case with multiple bony metastases☆
Abstract
Ameloblastic carcinoma is a rare primary tumor of the maxillofacial skeleton with a distinct predilection for the mandible. These lesions may initially show histologic features of ameloblastoma that dedifferentiate over time. Other ameloblastic carcinomas initially present with morphologic features suggestive of ameloblastoma with areas of epithelial dedifferentiation. We herein report a rare case of aggressive ameloblastic carcinoma in a 22-year-old white man who developed widespread bony metastases and expired 4 years after initial diagnosis. (Am J Otolaryngol 2003;24:64-69. Copyright 2003, Elsevier Science (USA). All rights reserved.)
From the Departments of *Head and Neck Surgery and †Surgical Pathology, Roswell Park Cancer Institute, Buffalo, NY
☆ Address correspondence to: Wesley L. Hicks Jr, MD, Department of Head and Neck, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263. E-mail: wesley.hicks@roswell park.org.
ABSTRACT