American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 27, Issue 1 , Pages 46-49, January 2006

Endoscopic sinus surgery for the treatment of chronic rhinosinusitis in patients with postirradiated nasopharyngeal carcinoma

Presented at the 19th Congress of the European Rhinologic Society, June 18, 2002, Ulm, Germany.

  • Mao-Chang Su, MD

      Affiliations

    • Department of Otolaryngology, Chung Shan Medical University Hospital, Taichung, Taiwan
    • Department of Medicine, Chung-Shan Medical University, Taichung, Taiwan
    • ,
  • Rong-San Jiang, MD

      Affiliations

    • Department of Medicine, Chung-Shan Medical University, Taichung, Taiwan
    • Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan
    • Corresponding Author InformationCorresponding author. Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan 40705, ROC. Tel.: +886 4 23592525 ext. 5401; fax: +886 4 23596868.
    • ,
  • Jung-Liang Chiang, EB

      Affiliations

    • Graduate Institute of Education, National Changhua University of Education, Changhua, Taiwan
    • ,
  • Jin-Ching Lin, MD

      Affiliations

    • Department of Radiation Oncology, Taichung Veterans General Hospital, Taichung, Taiwan

Received 21 March 2005

Abstract 

Purpose

Our purpose was to evaluate the efficacy and safety of endoscopic sinus surgery (ESS) in patients with nasopharyngeal carcinoma (NPC) after irradiation.

Materials and methods

A retrospective study of postirradiated NPC patients who received ESS for the treatment of chronic rhinosinusitis in Taichung Veterans General Hospital. Symptoms, endoscopic findings, and computed tomography were used to evaluate the efficacy of ESS in these patients, and the safety was evaluated by intraoperative findings and complications.

Results

Since 1996, 10 postirradiated NPC patients with chronic rhinosinusitis have been treated by ESS and followed up for at least 2 years. The interval between radiotherapy and ESS was from 4 months to 16 years. After surgery, 7 patients felt improved except for one patient who died of tumor recurrence and computed tomography scores changed from 6.6 to 3.7, although prolonged nasal crusting was observed in most patients by endoscopy. One patient was complicated with cerebrospinal fluid leakage and the dura defect was immediately repaired without any sequelae.

Conclusions

This study shows that ESS is effective for the treatment of chronic rhinosinusitis in postirradiated NPC patients if they failed medical treatment.

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S0196-0709(05)00136-5

doi:10.1016/j.amjoto.2005.07.007

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 27, Issue 1 , Pages 46-49, January 2006

Article Tools

* Image Usage & Resolution