American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 28, Issue 1 , Pages 28-30 , January 2007

Amoxicillin-clavulanic acid–induced hepatitis

  • Jason Cundiff, MD

      Affiliations

    • Corresponding Author InformationCorresponding author. University of Illinois, 4114 N. Kenmore #2N, Chicago, IL 60613. Tel.: +1 773 529 2384.
    • ,
  • Stephanie Joe, MD

Received 17 March 2006

References 

  1. Readin C, Cole M. Calvulanic acid: a beta-lactamase inhibiting beta-lactam from Streptomyces clavigerus. Antimicrob Agents Chemother. 1977;11:852–857
  2. Labia R, Peduzzi J. Kinetics of beta-lactamase inhibition by clavulanic acid. Biochim Biophys Acta. 1978;526:572–579
  3. Verhamme M, Ramboer C, Van De Bruaene P, et al. Cholestatic hepatitis due to an amoxicillin-clavulanic acid preparation. J Hepatol. 1989;9:260–264
  4. Schneider JE, Kleinman MS, Kupeic JW. Cholestatic hepatitis after treatment with amoxicillin-clavulanate potassium. N Y State J Med. 1989;89:355–356
  5. Dowsett JF, Gillow T, Heagerty A, et al. Amoxycillin-clavulanic acid (Augmentin) induced intrahepatic cholestasis. Dig Dis Sci. 1989;34:1290–1293
  6. Stricker BH, Van den Broek JW, Keuning J, et al. Cholestatic hepatitis due to antibacterial combination of amoxicillin and clavulanic acid (Augmentin). Dig Dis Sci. 1989;34:1576–1580
  7. Michielsen PP, Van Outryve MJ, Van Marck EA, et al. Amoxycillin/clavulanic acid induced cholestasis. J Hepatol. 1990;11:392
  8. Smith PM, Wilton A, Routledge PA. Jaundice associated with amoxicillin-clavulanate potassium therapy. Eur J Gastroenterol Hepatol. 1991;3:95–96
  9. Larrey D, Vial T, Micaleff A, et al. Hepatitis associated with amoxicillin-clavulanic acid combination report of 15 cases. Gut. 1992;33:368–371
  10. Ersoz G, Karasu Z, Yildiz C, et al. Severe toxic hepatitis associated with amoxicillin and clavulanic acid. J Clin Pharm Ther. 2001;26:225–229

PII: S0196-0709(06)00115-3

doi: 10.1016/j.amjoto.2006.06.007

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 28, Issue 1 , Pages 28-30 , January 2007

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