American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 28, Issue 4 , Pages 251-253, July 2007

Teflon granuloma results in a false-positive “second primary” on 18F-2-deoxyglucose positron emission tomography in a patient with a history of nasopharyngeal cancer

  • Jonathon L. Chadwick, BS

      Affiliations

    • Division of Otolaryngology—Head and Neck Surgery, Pennsylvania State University College of Medicine, Hershey, PA, USA
    • ,
  • Ayesha Khalid, MD

      Affiliations

    • Division of Otolaryngology—Head and Neck Surgery, Pennsylvania State University College of Medicine, Hershey, PA, USA
    • ,
  • Henry Wagner, MD

      Affiliations

    • Division of Radiation Oncology, Pennsylvania State University College of Medicine, Hershey, PA, USA
    • ,
  • Brendan C. Stack Jr., MD, FACS

      Affiliations

    • Department of Otolaryngology—Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    • Corresponding Author InformationCorresponding author. Department of Otolaryngology—Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA. Tel.: +1 501 686 5140; fax: +1 501 526 7153.

Received 13 July 2006

Abstract 

18F-2-deoxyglucose positron emission tomography (PET) is a frequent diagnostic tool used to evaluate patients with head and neck squamous cell carcinoma (HNSCC). 18F-2-deoxyglucose–PET is used in this setting for detection of metastases (staging) and/or second primaries. False-positive PET scans (10%-15% frequency) can distract from accurate HNSCC staging and an orderly prescription for treatment. Teflon (DuPont, Wilmington, DE) vocal fold injections can result in granuloma formation that has been described to generate a false-positive uptake on PET. We present a case of an injected vocal cord that appeared as a second laryngeal primary in a patient with recurrent nasopharyngeal cancer.

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PII: S0196-0709(06)00206-7

doi:10.1016/j.amjoto.2006.08.016

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 28, Issue 4 , Pages 251-253, July 2007

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