American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 28, Issue 5 , Pages 334-337 , September 2007

Nitric oxide: a new concept in chronic sinusitis pathogenesis

This article was first presented as a poster in the 50th annual meeting of the American Rhinologic Society, September 2004, New York. The continuation of the study led to its oral presentation in the Sixth Symposium of Experimental International Rhinology and Allergy of the Nose and the European Association of Allergology and Clinical Immunology (ENT section), February 2006, Barcelona.

  • Mohsen Naraghi, MD

      Affiliations

    • Iranian Rhinology Research Society, Department of Otorhinolaryngology, Head and Neck surgery & Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran
    • Corresponding Author InformationCorresponding author. No. 1281,Valie-Asr Avenue, Tehran 15178, Iran. Tel.: +98 21 8888 1376; fax: +98 21 8888 1376.
    • ,
  • Armin Farajzadeh Deroee, MD

      Affiliations

    • Iranian Rhinology Research Society, Department of Otorhinolaryngology, Head and Neck surgery & Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Tehran, Iran
    • ,
  • MohammadReza Ebrahimkhani, MD

      Affiliations

    • Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    • ,
  • Samira Kiani, MD

      Affiliations

    • Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    • ,
  • AhmadReza Dehpour, PhD

      Affiliations

    • Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

Received 22 August 2006

References 

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  3. Lunberg JON, Weitzberg E, Nordvall SL, et al. Primarily nasal origin of exhaled nitric oxide and absence in Kartagener's syndrome. Eur Respir J. 1994;7:150–154
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  18. Gaston B, Stamler JS. Nitrogen oxides. In:  Crystal RG,  West JB editor. The lung: scientific foundations. 2nd ed.. Philadelphia: Lippincott-Raven; 1997;p. 239–253
  19. Schlosser RJ, Spotnitz WD, Peters EJ, et al. Elevated nitric oxide metabolite levels in chronic sinusitis. 123:2000;357–362.
  20. Lindberg S, Cervin A, Runer T, et al. Nitric oxide production is decreased in upper airways is decreased in chronic sinusitis. Acta Otolaryngol (Stockh). 1994;117:113–117
  21. Baraldi E, Azzolin NM, Biban P, et al. Effect of antibiotic therapy on nasal nitric oxide concentration in children with acute sinusitis. Am J Respir Crit Care Med. 1997;155:1680–1683
  22. Miranda KM, Espey MG, Wink DA. A rapid simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide. 2001;5(1):62–71
  23. Deja M, Busch T, Bachmann S, et al. Reduced nitric oxide in sinus epithelium of patients with radiologic maxillary sinusitis and sepsis. Am J Respir Crit Care Med. 2003;168:281–286
  24. Ho LP, Innes JA, Greening AP. Nitrite levels in breath condensate of patients with cystic fibrosis is elevated in contrast to exhaled nitric oxide. Thorax. 1998;53:680–684
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☆ This study was financially supported by the Tehran University of Medical Sciences Vice Chancellor for Research.

PII: S0196-0709(06)00261-4

doi: 10.1016/j.amjoto.2006.10.014

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 28, Issue 5 , Pages 334-337 , September 2007

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