American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 29, Issue 1 , Pages 63-65 , January 2008

Unintended benefits of immunosupression on autoimmune disease due to chemoradiation therapy for head and neck cancer

  • Mohammed Iqbal Syed, MS, MRCS

      Affiliations

    • Royal Alexandra Hospital, Greater Glasgow & Clyde Hospitals NHS Trust, Glasgow, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 7792124133; fax: +44 1413327519.
    • ,
  • Louise J. Clark, MD, FRCS

      Affiliations

    • Southern General Hospital, Greater Glasgow & Clyde Hospitals NHS Trust, Glasgow, UK
    • ,
  • Roger D. Sturrock, MD, URCP, FRCP

      Affiliations

    • University Department of Medicine, Glasgow Royal Infirmary University Trust, Glasgow, UK

Received 26 May 2006

References 

  1. Bunch TW, Erlichman C, Luthra HS, et al. An open-label, phase I/II study of 5-flouorouracil plus leucovorin in the treatment of rheumatoid arthritis. J Rheumatol. 2002;29(5):1109–1110
  2. Jensen AO, Mejer J. Remission of methotrexate-resistant rheumatoid arthritis after receiving 5-Flouorouracil for colon cancer. J Intern Med. 2003;254(4):395–396
  3. Mathews CK, van Holde KE. Nucleotide metabolism. In:  Mathews CK,  van Holde KE editor. Biochemistry. San Francisco, CA: Benjamin Cummings Publishing Company; 1990;p. 742–747
  4. Mathews CK, van Holde KE. Information restructuring. In:  Mathews CK,  van Holde KE editor. Biochemistry. San Francisco, CA: Benjamin Cummings Publishing Company; 1990;p. 670–702
  5. Mathews CK, van Holde KE. Metabolism of nitrogenous compounds. In:  Mathews CK,  van Holde KE editor. Biochemistry. San Francisco, CA: Benjamin Cummings Publishing Company; 1990;p. 860–896
  6. Stern RS, Laird N, Melski J, et al. Cutaneous squamous-cell carcinoma in patients treated with PUVA. N Engl J Med. 1984;310:1156–1161
  7. Stern RS, Laird N. The carcinogenic risks for treatment for severe psoriasis. Photochemotherapy follow up study. Cancer. 1994;73:2759–2764
  8. Lever LR, Farr PM. Skin cancer or premalignant lesions occur in half of high-dose PUVA patients. Br J Dermatol. 1994;131:215–219
  9. Lindelof B, Sigurgeirsson B, Tegner E, et al. PUVA and cancer: a large-scale epidemiological study. Lancet. 1991;338:91–93
  10. Lindelof B, Sigurgeirusson B, Tegner E, et al. PUVA and cancer risk: the Swedish follow-up study. Br J Dermatol. 1999;141:108–112
  11. Lim JL, Stern RS. High levels of ultraviolet B exposure increase the risk of non-melanoma skin cancer in psoralen and ultraviolet A treated patients. J Invest Dermatol. 2005;124(3):505–513
  12. Meggitt SJ, Reynolds NJ. Azathioprine for atopic dermatitis. Clin Exp Dermatol. 2001;26(5):369–375
  13. Bottomley WW, Ford G, Cunliffe WJ. Aggressive squamous cell carcinomas developing in patients receiving long-term azathioprine. Br J Dermatol. 1995;133(3):460–462
  14. Lewis P, Hazleman BL, Hanka R, et al. Cause of death in patients with rheumatoid arthritis with particular reference to azathioprine. Ann Rheum Dis. 1980;39:457
  15. Guba M, Graeb C, Jauch KW, et al. Pro- and anti-cancer effects of immunosuppressive agents used in organ transplantation. Transplantation. 2004;77(12):1777–1782
  16. Dalton A, Curtis D, Harrington CI. Synergistic effects of azathioprine and ultraviolet light detected by sister chromatid exchange analysis. Cancer Genet Cytogenet. 1990;45(1):93–99
  17. Jansen GT. Grenz rays: adequate or antiquated?. J Dermatol Surg Oncol. 1978;4(8):627–629
  18. Stambaugh MD, DeNittis AS, Wallner PE, et al. Complete remission of refractory dyshidrotic eczema with the use of radiation therapy. Cutis Chatham. 2000;65(4):211–214

PII: S0196-0709(07)00009-9

doi: 10.1016/j.amjoto.2007.01.005

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 29, Issue 1 , Pages 63-65 , January 2008

Article Tools