Endonasal transsphenoidal pituitary surgery: is tumor volume a key factor in determining outcome?

Jain, Amit Kumar; Gupta, Ashok Kumar; Pathak, Ashis; Bhansali, Anil; Bapuraj, J. Rajiv

doi:10.1016/j.amjoto.2007.01.006

« Previous Next »American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 29, Issue 1 , Pages 48-50, January 2008

Endonasal transsphenoidal pituitary surgery: is tumor volume a key factor in determining outcome?

Amit Kumar Jain, MS
- Department of Otolaryngology & Head & Neck surgery, Post-Graduate Institute of Medical Education and Research, Chandigarh, India
Ashok Kumar Gupta, MS
- Department of Otolaryngology & Head & Neck surgery, Post-Graduate Institute of Medical Education and Research, Chandigarh, India
- Corresponding author. Department of ENT, 5th Floor, ‘B’ block, PGIMER, Sector 12, Chandigarh, India. Tel.: +91 9814198850.
Ashis Pathak, MS, MCh
- Department of Neurosurgery, Post-Graduate Institute of Medical Education and Research, Chandigarh, India
Anil Bhansali, MD, DM
- Department of Endocrinology, Post-Graduate Institute of Medical Education and Research, Chandigarh, India
J. Rajiv Bapuraj, MD
- Department of Radiodiagnosis and Imaging, Post-Graduate Institute of Medical Education and Research, Chandigarh, India

Received 30 August 2006

Abstract

Purpose

This study was conducted to evaluate the role of tumor volume in excision of pituitary adenomas.

Materials and methods

A total of 20 patients with pituitary adenoma underwent surgical excision of the tumor by endonasal transsphenoidal approach.

Results

A preoperative tumor volume of more than 5 mL is associated with a 90.90% probability of residual tumor (P < .05, statistically significant).

Conclusion

Tumor volume as a predicting factor for the surgical outcome is an evolving concept. Other factors determining the efficacy of tumor removal are parasellar and suprasellar extension.