American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 29, Issue 3 , Pages 201-204 , May 2008

Langerhans cell histiocytosis of the thyroid gland

  • Kevin Lollar, MD

      Affiliations

    • Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA
    • ,
  • Tarik Y. Farrag, MD

      Affiliations

    • Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA
    • ,
  • Dengfeng Cao, MD, PhD

      Affiliations

    • Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA
    • ,
  • John Niparko, MD

      Affiliations

    • Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA
    • ,
  • Ralph P. Tufano, MD

      Affiliations

    • Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 410 955 3628; fax: +1 410 614 8610.

Received 9 March 2007

References 

  1. Favara BE, Feller AC, Pauli M, et al. Contemporary classification of histiocytic disorders. The WHO Committee On Histiocytic/Reticulum Cell Proliferations. Reclassification Working Group of the Histiocyte Society. Med Pediatr Oncol. 1997;29(3):157–166
  2. Coppes-Zantinga A, Egeler RM. The Langerhans cell histiocytosis X files revealed. Br J Haematol. 2002;116:3
  3. McClain K, Jin H, Gresik V, et al. Langerhans cell histiocytosis: lack of a viral etiology. Am J Hematol. 1994;47:16
  4. McClain KL, Laud P, Wu WS, et al. Langerhans cell histiocytosis patients have HLA Cw7 and DR4 types associated with specific clinical presentations and no increased frequency in polymorphisms of the tumor necrosis factor alpha promoter. Med Pediatr Oncol. 2003;41:502
  5. Shimakage M, Sasagawa T, Kimura M, et al. Expression of Epstein-Barr virus in Langerhans' cell histiocytosis. Hum Pathol. 2004;35:862
  6. Egeler RM, Favara BE, van Meurs M, et al. Differential in situ cytokine profiles of Langerhans-like cells and T cells in Langerhans cell histiocytosis: abundant expression of cytokines relevant to disease and treatment. Blood. 1999;94:4195
  7. Behrens RJ, Levi AW, Westra WH, et al. Langerhans cell histiocytosis of the thyroid: a report of two cases and review of the literature. Thyroid. 2001;11(7):697–705
  8. Wang WS, Liu JH, Chiou TJ, et al. Langerhans' cell histiocytosis with thyroid involvement masquerading as thyroid carcinoma. Jpn J Clin Oncol. 1997;27(3):180–184
  9. Farrag TY, Lin FR, Cummings CW, et al. Importance of routine evaluation of thyroid gland prior to open partial laryngectomy. Arch Otolaryngol Head Neck Surg. 2006;132:1047–1051
  10. Seiji M, Shimao K, Fitzpatrick TB, et al. The site of biosynthesis of mammalian tyrosinase. J Invest Dermatol. 1961;37:359
  11. Elliott DD, Sellin R, Egger JF, et al. Langerhans cell histiocytosis presenting as a thyroid gland mass. Ann Diagn Pathol. 2005;9(5):267–274
  12. Broadbent V, Gadner H. Current therapy for Langerhans cell histiocytosis. Hematol Oncol Clin North Am. 1998;12:327–338

☆ All of the authors had contributed to, read, and approved the manuscript.

☆☆ The authors had consent from the patient to report her case.

PII: S0196-0709(07)00082-8

doi: 10.1016/j.amjoto.2007.05.004

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 29, Issue 3 , Pages 201-204 , May 2008

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