American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 29, Issue 6 , Pages 398-402 , November 2008

Induction with T-cell receptor antibody leads to long-term laryngeal allograft function

  • P. Daniel Knott, MD

      Affiliations

    • Corresponding Author InformationCorresponding author. Head and Neck Institute, The Cleveland Clinic Foundation, Desk A-71, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Tel.: +1 216 444 6686; fax: +1 216 445 9409.
  • ,
  • Olivia Dan, BS
  • ,
  • Marshall Strome, MD, MS

Received 26 November 2007

References 

  1. Siemionow M, et al. Induction of tolerance in composite-tissue allografts. Transplantation. 2002;74(9):1211–1217
  2. Yamagami S, et al. Suppression of allograft rejection with anti–αβ T cell receptor antibody in rat corneal transplantation. Transplantation. 1999;67(4):600–604
  3. Tsuchida M, et al. Induction of specific unresponsiveness to cardiac allografts by short-term administration of anti–T cell receptor αβ antibody. Transplantation. 1994;57(2):256–262
  4. Knight RJ, Kurrle R, Stepkowski S, et al. Synergistic immunosuppressive actions of cyclosporine with a mouse anti-rat α/β-T cell receptor monoclonal antibody. Transplantation. 1994;57:1544
  5. Heidecke CD, Hancock WW, Westerholt S, et al. α/β-T cell receptor–directed therapy in rat allograft recipients. Transplantation. 1996;61:948
  6. Hammano K, et al. Anti–αβ-T cell receptor monoclonal antibody induces tolerance without dominant infiltration by TH2 cells into grafts. Transplant Proc. 1998;30:3892
  7. Nelson M, Dan O, Strome M. Evaluation of parathyroid hormone as a functional biological marker of rat laryngeal transplant rejection. Laryngoscope. 2003;113:1483–1486
  8. Lorenz RR, et al. Rat laryngeal transplant model: technical advancements and a redefined rejection grading system. Ann Otol Rhinol Laryngol. 2002;111:1120–1127
  9. Akst L, Siemionow M, Dan O, et al. Induction of tolerance in a rat model of laryngeal transplantation. Transplantation. 2003;76(12):1763–1770
  10. Nelson M, Fritz M, Dan O, et al. Tacrolimus and mycophenolate mofetil provide effective immunosuppression in rat laryngeal transplantation. Laryngoscope. 2003;113:1308–1313

PII: S0196-0709(08)00003-3

doi: 10.1016/j.amjoto.2007.12.004

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 29, Issue 6 , Pages 398-402 , November 2008