American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 30, Issue 2 , Pages 121-133, March 2009

Nonmelanoma skin cancer of the head and neck I: histopathology and clinical behavior

  • John F. McGuire, MD, MBA

      Affiliations

    • Department of Otolaryngology, Head and Neck Surgery, University of California, Irvine, CA, USA
    • ,
  • Norman N. Ge, MD, FACS

      Affiliations

    • Department of Otolaryngology, Head and Neck Surgery, University of California, Irvine, CA, USA
    • Corresponding Author InformationCorresponding author. Department of Otolaryngology, Head and Neck Surgery, University of California, Irvine, 16300 Sand Canyon Ave, Suite 201, Irvine, CA 92618, USA. Tel.: +1 949 727 1818; fax: +1 949 727 1819.
    • ,
  • Senait Dyson, MD

      Affiliations

    • Department of Dermatology, University of California, Irvine, CA, USA

Received 14 January 2008 published online 24 July 2008.

Abstract 

Non-Melanoma skin cancer (NMSC) is the most commonly encountered malignancy in almost every area of practice, but the cases that present to an Otolaryngology practice will be advanced in nature. The major subtypes of NMSC include basal cell carcinoma, squamous cell carcinoma, dermatofibrosarcoma protuberans, merkel cell carcinoma, and adnexal malignancies. In this review, we present the epidemiology, histology, clinical presentation and management of these major subtypes. Further, we present background on multimodality treatment for NMSC lesions that have become metastatic from their primary site and an introduction to the behavior and treatment of NMSC lesions in patients who have received organ transplants. Understanding the clinical behavior of advanced NMSC is essential knowledge for a general Otolaryngologist.

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PII: S0196-0709(08)00046-X

doi:10.1016/j.amjoto.2008.03.002

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 30, Issue 2 , Pages 121-133, March 2009

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