American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 31, Issue 2 , Pages 127-129, March 2010

Necrotizing fasciitis secondary to bisphosphonate-induced osteonecrosis of the jaw

  • Dhave Setabutr, BED

      Affiliations

    • Texas Tech University Health Sciences Center, Amarillo, TX, USA
  • ,
  • Nathan W. Hales, MD

      Affiliations

    • Department of Otorhinolaryngology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
  • ,
  • Greg A. Krempl, MD

      Affiliations

    • Department of Otorhinolaryngology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
    • Corresponding Author InformationCorresponding author. Department of Otorhinolaryngology, Head and Neck Surgery, University of Oklahoma Medical Center, 920 Stanton L. Young, WP 1290, Oklahoma City, OK 73190, USA. Tel.: +1 405 271 5504; fax: +1 405 271 3248.

Received 16 July 2008 published online 27 March 2009.

Abstract 

Osteonecrosis of the jaw is an uncommon consequence of biphosphonate therapy. This has most commonly been a bone complication with little if any soft tissue involvement. An unusual case of necrotizing fasciitis with extensive soft tissue infection stemming from a prolonged case of osteonecrosis of the jaw presented. The management of this patient (aggressive surgical debridement and prolonged wound care) is reviewed as well as the review of the underlying processes.

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PII: S0196-0709(08)00234-2

doi:10.1016/j.amjoto.2008.11.002

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 31, Issue 2 , Pages 127-129, March 2010