American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 31, Issue 6 , Pages 479-481 , November 2010

Spurious decline in intraoperative parathyroid hormone: false positives in parathyroid surgery

  • Doug Sidell, MD

      Affiliations

    • Corresponding Author InformationCorresponding author. Division of Head and Neck Surgery, David Geffen School of Medicine at UCLA, 10833 Le Conte Ave. 62-132 CHS, Los Angeles, CA 90095-1624, USA. Tel.: +1 202 316 4433.
    • ,
  • John Wang, BS
    • ,
  • Joel Sercarz, MD

Received 2 June 2009

References 

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  2. Nussbaum SR, Thompson AR, Hutcheson KA, et al. Intraoperative measurement of parathyroid hormone in surgical management of hyperparathyroidism. Surgery. 1988;104:1121–1127
  3. Gauger PG, Agarwal G, England BG, et al. Intraoperative parathyroid hormone monitoring fails to detect double parathyroid adenomas: a 2-institution experience. Surgery. 2001;130:1005–1010
  4. Carneiro DM, Irvin GL. New point-of-care intraoperative parathyroid hormone assay for intraoperative guidance in parathyroidectomy. World J Surg. 2002;16:1074–1077
  5. Irvin GL, Solorzano CC, Carnerio DM. Quick intraoperative parathyroid hormone assay: surgical adjunct to allow limited parathyroidectomy, improve success rate, and predict outcome. World J. Surg. 2004;28:1287–1292
  6. Riss P, Kaczirek K, Heinz G, et al. A “defined baseline” in PTH monitoring increases surgical success in patients with multiple gland disease. Surgery. 2007;142:398–404
  7. Carneiro DM, Solorzano CC, Nader MC, et al. Comparison of intraoperative iPTH assay (QPTH) criteria in guiding parathyroidectomy: which criterion is the most accurate?. Surgery. 2003;134:973–981
  8. Lombardi CP, Raffaelli M, Traini E, et al. Intraoperative PTH monitoring during parathyroidectomy; the need for stricter criteria to detect multiglandular disease. Langenbecks Arch Surg. 2008;393:639–645
  9. Lupoli GA, Fonderico F, Panico A, et al. Stricter criteria increase the validity of a quick intraoperative parathyroid hormone assay in primary hyperparathyroidism. Med Sci Monit. 2009;15:111–116
  10. Horányi J, Duffek L, Szlávik R, et al. Parathyroid surgical failures with misleading falls of intraoperative parathyroid hormone levels. J Endocrinol Invest. 2003;26:1095–1099
  11. Irvin GL, Molinari AS, Figureoa C, et al. Improved success rate in reoperative parathyroidectomy with intraoperative PTH assay. Ann Surg. 1999;229:874–878
  12. Garon JE, Liu N. Recent advances in parathyroid disease and parathyroid hormone assays. Clin Leadersh Manag Rev. 2002;16:187–191
  13. Yamishita H, Gao P, Noguchi S, et al. Role of cyclase activating parathyroid hormone (1-84 PTH) measurements during parathyroid surgery: potential improvement of intraoperative PTH assay. Ann Surg. 2002;236:105–111
  14. Dewan AK, Kapadia SB, Hollenbeak CS, et al. Is routine frozen section necessary for parathyroid surgery?. Otolaryngol Head Neck Surg. 2005;133:857–862

PII: S0196-0709(09)00132-X

doi: 10.1016/j.amjoto.2009.07.003

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 31, Issue 6 , Pages 479-481 , November 2010

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