American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 31, Issue 6 , Pages 448-452 , November 2010

Age-related changes in the hyoepiglottic ligament: functional implications based on histopathologic study

  • Motohiro Sawatsubashi, MD, PhD

      Affiliations

    • Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyushu University, Fukuoka, Japan
    • Corresponding Author InformationCorresponding author. Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyushu University, Fukuoka 812-8582, Japan. Tel.: +81 92 642 5668; fax: +81 92 5685.
    • ,
  • Toshiro Umezaki, MD, PhD

      Affiliations

    • Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyushu University, Fukuoka, Japan
    • ,
  • Kenichiro Kusano, MD, PhD

      Affiliations

    • Department of Pathology, Saga Medical School, Saga, Japan
    • ,
  • Osamu Tokunaga, MD, PhD

      Affiliations

    • Department of Pathology, Saga Medical School, Saga, Japan
    • ,
  • Masamichi Oda, MD, PhD

      Affiliations

    • ENT Surgery Center, Yuai-Kai Oda Hospital Kashima, Saga, Japan
    • ,
  • Shizuo Komune, MD, PhD

      Affiliations

    • Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyushu University, Fukuoka, Japan

Received 21 April 2009

References 

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  2. Ekberg O, Sigurjonsson SV. Movement of the epiglottis during deglutition. A cineradiographic study. Gastrointest Radiol. 1982;7:101–107
  3. Ekberg O. Epiglottic dysfunction during deglutition in patients with dysphagia. Arch Otolaryngol. 1983;109:376–380
  4. Pernkof . Head and neck. In:  Werner P editors. Pernkof anatomy. vol. 1:Baltimore-Munich: Urban & Schwarzenberg; 1989;p. 323;325
  5. Sobotta . Head, neck, upper limb. In:  Putz R,  Pabst R editor. 12th ed. Atlas of human anatomy. Vol. 1:Baltimore: Williams & Wilkins; 1997;p. 121–126
  6. Zeitels SM, Kirchner JA. Hyoepiglottic ligament in supraglottic cancer. Ann Otol Rhinol Laryngol. 1995;104:770–775
  7. Vandaele DJ, Perlman AL, Cassell MD. Intrinsic fiber architecture and attachments of the human epiglottis and their contributions to the mechanism of deglutition. J Anat. 1995;186:1–15
  8. Reidenbach MM. The periepiglottic space: tomographic relations and histological organisation. J Anat. 1996;188:173–182
  9. Sawatsubashi M, Mizokami Y, Tokunaga O, et al. Expression of MMP-1, TIMP-1, and type I collagen in laryngeal carcinoma. Mod Pathol. 1998;11:878–885
  10. Ekberg O. The normal movements of the hyoid bone during swallow. Invest Radiol. 1986;21:408–410
  11. Garon BR, Huang Z, Hommeyer M, et al. Epiglottic dysfunction: abnormal epiglottic movement patterns. Dysphagia. 2002;17:57–68
  12. Gazayerli M, Bleibel W, Elhorr A, et al. A correlation between the shape of the epiglottis and obstructive sleep apnea. Surg Endosc. 2006;20:836–837
  13. Pierce RJ, Worsnop CJ. Upper airway function and dysfunction in respiration. Clin Exp Pharmacol Physiol. 1999;26:1–10
  14. Horner RL, Innes JA, Holden HB, et al. Afferent pathway(s) for pharyngeal dilator reflex to negative pressure in man: a study using upper airway anaesthesia. J Physiol (Lond). 1991;436:31–44
  15. Kletzker GR, Bastian RW. Acquired airway obstruction from histologically normal, abnormally mobile supraglottic soft tissues. Laryngoscope. 1990;100:375–379
  16. Bailey EF, Fregosi RF. Coordination of intrinsic and extrinsic tongue muscles during spontaneous breathing in the rat. J Appl Physiol. 2004;96:440–449
  17. Alan J. Sokoloff. Activity of tongue muscles during respiration: it takes a village?. J Appl Physiol. 2004;96:438–439
  18. Rower JJ, Moore GV, Hamilton P. Acquired laryngomalacia: epiglottis prolapse as a cause of airway obstruction. Ann Otol Rhinol Laryngol. 1993;102:485–486
  19. Valera FC, Tamashiro E, de Araujo MM. Evaluation of the efficacy of supraglottoplasty in obstructive sleep apnea syndrome associated with severe laryngomalacia. Arch Otolaryngol Head Neck Surg. 2006;132:489–493

☆ This work was presented in part at the AAO-HNSF Annual Meeting, Toronto, Ontario, Canada, on September 17–20, 2006.

PII: S0196-0709(09)00163-X

doi: 10.1016/j.amjoto.2009.08.003

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 31, Issue 6 , Pages 448-452 , November 2010

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