American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 32, Issue 3 , Pages 235-239 , May 2011

Effects of sulfurous, salty, bromic, iodic thermal water nasal irrigations in nonallergic chronic rhinosinusitis: a prospective, randomized, double-blind, clinical, and cytological study

  • Giancarlo Ottaviano, MD

      Affiliations

    • Otolaryngology Section, Department of Medical and Surgical Specialties, University of Padova, Padova, Italy
    • ,
  • Gino Marioni, MD

      Affiliations

    • Otolaryngology Section, Department of Medical and Surgical Specialties, University of Padova, Padova, Italy
    • ,
  • Claudia Staffieri, MD

      Affiliations

    • Otolaryngology Section, Department of Medical and Surgical Specialties, University of Padova, Treviso, Italy
    • ,
  • Luciano Giacomelli, BD

      Affiliations

    • Anatomic Pathology Section, Department of Medical/Diagnostic Sciences and Special Therapies, University of Padova, Padova, Italy
    • ,
  • Rosario Marchese-Ragona, MD

      Affiliations

    • Otolaryngology Section, Department of Medical and Surgical Specialties, University of Padova, Padova, Italy
    • ,
  • Andy Bertolin, MD

      Affiliations

    • Otolaryngology Section, Department of Medical and Surgical Specialties, University of Padova, Padova, Italy
    • ,
  • Alberto Staffieri, MD

      Affiliations

    • Otolaryngology Section, Department of Medical and Surgical Specialties, University of Padova, Padova, Italy
    • Corresponding Author InformationCorresponding author. Otolaryngology Section, Department of Medical and Surgical Specialties, Via Giustiniani 2, 35128 Padova, Italy. Tel.: +39 0 49 8212010; fax: +39 0 49 8213113.

Received 1 November 2009

References 

  1. Berger G, Kattan A, Bernheim J, et al. Polypoid mucosa with eosinophilia and glandular hyperplasia in chronic sinusitis: a histopathological and immunohistochemical study. Laryngoscope. 2002;112:738–745
  2. Hamilos DL. Chronic sinusitis. J Allergy Clin Immunol. 2000;106:213–227
  3. Benninger MS, Anon J, Mabry RL. The medical management of chronic rhinosinusitis. Otolaryngol Head Neck Surg. 1997;117:541–559
  4. Rabago D, Pasic T, Zgierska A, et al. The efficacy of hypertonic saline nasal irrigation for chronic sinonasal symptoms. Otolaryngol Head Neck Surg. 2005;133:3–8
  5. Rabago D, Zgierska A, Mundt M, et al. Efficacy of daily hypertonic saline nasal irrigation among patients with sinusitis: a randomized controlled trial. J Fam Pract. 2002;51:1049–1055
  6. Talbot AR, Herr TM, Parsons DS. Mucociliary clearance and buffered hypertonic saline solution. Laryngoscope. 1997;107:500–503
  7. Inanli S, Ozturk O, Korkmaz M, et al. The effects of topical agents of fluticasone proprionate, oxymetazoline, and 3% and 0.9% sodium chloride solutions on mucociliary clearance in the therapy of acute bacterial rhinosinusitis in vivo. Laryngoscope. 2002;12:320–325
  8. Staffieri A, Abramo A. Sulphurous-arsenical-ferruginous (thermal) water inhalations reduce nasal respiratory resistance and improve mucociliary clearance in patients with chronic sinonasal disease: preliminary outcomes. Acta Otolaryngol. 2007;127:613–617
  9. Brown CL, Graham SM. Nasal irrigation: good or bad?. Curr Opin Head Neck Surg. 2004;12:9–13
  10. Staffieri A, Miani C, Bergamin AM, et al. Effect of sulphurous-salty-bromic-iodic thermal waters on albumin and IgA concentrations in nasal secretions. Acta Otorhinolaryngol Ital. 1998;18:233–238
  11. Gelardi M, Cassano P, Cassano M, et al. Nasal cytology: description of a hyperchromatic supranuclear stria as a possible marker for the anatomical and functional integrity of the ciliated cell. Am J Rhinol. 2003;17:263–268
  12. Schleimer RP, Kato A, Kern R, et al. Epithelium: at the interface of innate and adaptive immune responses. J Allergy Clin Immunol. 2007;120:1279–1284
  13. Staffieri A, Marino F, Staffieri C, et al. The effect of sulphurous-arsenical-ferruginous thermal water nasal irrigation in wound healing after functional endoscopic sinus surgery for chronic rhinosinusitis: a prospective randomized study. Am J Otolaryngol. 2008;29:223–229
  14. Aslani FS, Khademi B, Yeganeh F, et al. Nasal cytobrush cytology: evaluation of the hyperchromatic supranuclear stria. Acta Cytol. 2006;50:430–434
  15. Zerdiew A, Mazzarella R, Vargas DV, et al. Supranuclear stria of ciliated cells in allergic rhinitis. Medicina. 2007;67:360–362

PII: S0196-0709(10)00041-4

doi: 10.1016/j.amjoto.2010.02.004

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 32, Issue 3 , Pages 235-239 , May 2011

Article Tools

* Image Usage & Resolution