American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 33, Issue 1 , Pages 14-19 , January 2012

Similar cellular proliferation activities in nasal polyps and adjacentinferior turbinate

  • Chia-Chen Wu, MD

      Affiliations

    • Department of Otolaryngology – Head and Neck Surgery, Chang Gung Memorial Hospital, Kwei-Shan, Tao-Yuan, Taiwan
    • ,
  • Ta-Jen Lee, MD

      Affiliations

    • Department of Otolaryngology – Head and Neck Surgery, Chang Gung Memorial Hospital, Kwei-Shan, Tao-Yuan, Taiwan
    • ,
  • Po-Hung Chang, MD

      Affiliations

    • Department of Otolaryngology – Head and Neck Surgery, Chang Gung Memorial Hospital, Kwei-Shan, Tao-Yuan, Taiwan
    • Graduate Institute of Clinical Medical Sciences, Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan
    • ,
  • Chi-Neu Tsai, PhD

      Affiliations

    • Graduate Institute of Clinical Medical Sciences, Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan
    • ,
  • Yun-Shien Lee, PhD

      Affiliations

    • Genomic Medicine Research Core Laboratory, Chang Gung Memorial Hospital, Kwei-Shan, Tao-Yuan, Taiwan
    • Department of Biotechnology, Ming-Chuan University, Kwei-Shan, Tao-Yuan, Taiwan
    • ,
  • Chia-Hsiang Fu, MD

      Affiliations

    • Department of Otolaryngology – Head and Neck Surgery, Chang Gung Memorial Hospital, Kwei-Shan, Tao-Yuan, Taiwan
    • ,
  • Chi-Che Huang, MD

      Affiliations

    • Department of Otolaryngology – Head and Neck Surgery, Chang Gung Memorial Hospital, Kwei-Shan, Tao-Yuan, Taiwan
    • Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Keelung, Chang Gung University, Taoyuan, Taiwan
    • Corresponding Author InformationCorresponding author. Department of Otolaryngology – Head and Neck Surgery, Chang Gung Memorial Hospital, Kwei-Shan, Tao-Yuan, Taiwan No 5, Fu Hsing Street, Kwei-Shan, Taoyuan 333, Taiwan. Tel.: +886 3 3281200x8466; fax: +886 3 3271244.

Received 28 June 2010

References 

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  2. Karin M, Liu ZG, Zandi E. AP-1 function and regulation. Curr Opin Cell Biol. 1997;9:240–246
  3. Shaulian E, Karin M. AP-1 in cell proliferation and survival. Oncogene. 2001;20:2390–2400
  4. Connolly KM, Bogdanffy MS. Evaluation of proliferating cell nuclear antigen (PCNA) as an endogenous marker of cell proliferation in rat liver: a dual-stain comparison with 5-bromo-2′-deoxyuridine. J Histochem Cytochem. 1993;41:1–6
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  10. Bhattacharyya N. Chronic rhinosinusitis: is the nose really involved?. Am J Rhinol. 2001;15:169–173
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  14. Jankowski R, Bouchoua F, Coffinet L, et al. Clinical factors influencing the eosinophil infiltration of nasal polyps. Rhinology. 2002;40:173–178
  15. Pegorier S, Wagner LA, Gleich GJ, et al. Eosinophil-derived cationic proteins activate the synthesis of remodeling factors by airway epithelial cells. J Immunol. 2006;177:4861–4869
  16. Eweiss A, Dogheim Y, Hassab M, et al. VCAM-1 and eosinophilia in diffuse sino-nasal polyps. Eur Arch Otorhinolaryngol. 2009;266:377–383
  17. Ackerman SJ, Bochner BS. Mechanisms of eosinophilia in the pathogenesis of hypereosinophilic disorders. Immunol Allergy Clin North Am. 2007;27:357–375
  18. Valera FC, Queiroz R, Scrideli C, et al. Expression of transcription factors NF-kappaB and AP-1 in nasal polyposis. Clin Exp Allergy. 2008;38:579–585
  19. Almawi WY, Melemedjian OK. Negative regulation of nuclear factor-kappaB activation and function by glucocorticoids. J Mol Endocrinol. 2002;28:69–78
  20. Busaba NY, Shin HJ, Faquin WC. Correlation between middle turbinate and ipsilateral ethmoid histopathology in chronic rhinosinusitis. Otolaryngol Head Neck Surg. 2006;134:250–254

PII: S0196-0709(10)00252-8

doi: 10.1016/j.amjoto.2010.12.001

American Journal of Otolaryngology - Head and Neck Medicine and Surgery
Volume 33, Issue 1 , Pages 14-19 , January 2012

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